Desoxycorticosterone Pivalate
Desoxycorticosterone Pivalate is a long-acting mineralocorticoid ester used primarily in veterinary medicine to treat adrenal insufficiency and related conditions. It works by promoting sodium retention and potassium excretion in the kidneys, helping maintain electrolyte balance and blood pressure. This medication is particularly valuable for managing chronic conditions requiring sustained mineralocorticoid replacement therapy.
Desoxycorticosterone Pivalate is a mineralocorticoid used to treat adrenal insufficiency by helping maintain proper sodium and potassium balance in the body.
Key facts at a glance
- RxNorm
- 22537
- Generic
- Desoxycorticosterone Pivalate
- Class
- pin-variant
- Brands
- Zycortal
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
This medication is primarily used to treat hypoadrenocorticism (Addison's disease) and other conditions involving mineralocorticoid deficiency. It helps manage the salt-wasting form of adrenal insufficiency where the body cannot adequately retain sodium and eliminate potassium.
As a mineralocorticoid, it binds to mineralocorticoid receptors in the distal tubules and collecting ducts of the kidneys. This activation increases expression of sodium channels and Na+/K+-ATPase pumps, promoting sodium reabsorption and potassium excretion to help maintain proper electrolyte balance and blood volume.
Regular monitoring of electrolyte levels and clinical signs is essential during treatment. Overdosing may lead to sodium retention, fluid overload, hypertension, or dangerously low potassium levels. This medication is typically administered as an injectable depot formulation, providing sustained release over several weeks. Always follow veterinary prescribing guidelines closely.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy