Desvenlafaxine Fumarate Monohydrate
Desvenlafaxine Fumarate Monohydrate is an antidepressant medication classified as a serotonin-norepinephrine reuptake inhibitor (SNRI). It is primarily prescribed for the treatment of major depressive disorder (MDD) in adults. The medication works by increasing the levels of serotonin and norepinephrine in the brain, which are neurotransmitters associated with mood regulation.
Desvenlafaxine is an SNRI antidepressant used to treat major depressive disorder by increasing serotonin and norepinephrine levels in the brain.
Key facts at a glance
- RxNorm
- 1487366
- Generic
- Desvenlafaxine Fumarate Monohydrate
- Class
- pin-variant
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Desvenlafaxine Fumarate Monohydrate is FDA-approved for the treatment of major depressive disorder (MDD) in adults. It may also be used off-label for other conditions as determined by a healthcare provider.
As an SNRI, this medication works by inhibiting the reuptake (reabsorption) of both serotonin and norepinephrine neurotransmitters in the brain. By preventing their reuptake, it increases the availability of these chemicals in the synaptic space, which helps improve mood and reduce symptoms of depression.
Desvenlafaxine should not be discontinued abruptly, as this may cause withdrawal symptoms. It carries warnings for increased risk of suicidal thoughts in young adults, children, and adolescents. Common side effects may include nausea, dry mouth, and dizziness. Patients should inform their doctor of any history of bipolar disorder, seizures, or liver problems before starting treatment.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy