Deuruxolitinib Phosphate
Deuruxolitinib phosphate is an oral Janus kinase (JAK) inhibitor used for the treatment of moderate-to-severe alopecia areata in adult patients. It works by targeting JAK1 and JAK2 enzymes involved in inflammatory pathways that drive hair loss. This medication was developed as a deuterated form of ruxolitinib and represents a targeted therapeutic option for patients seeking treatment for autoimmune-related hair loss.
Deuruxolitinib phosphate is a JAK inhibitor oral medication approved for treating moderate-to-severe alopecia areata in adults.
Key facts at a glance
- RxNorm
- 2716557
- Generic
- Deuruxolitinib Phosphate
- Class
- pin-variant
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment of moderate-to-severe alopecia areata in adult patients, including patchy hair loss and totalis/universalis variants.
Acts as a selective Janus kinase (JAK) inhibitor, primarily targeting JAK1 and JAK2 to interrupt inflammatory signaling pathways that contribute to hair follicle immune privilege disruption and subsequent hair loss.
May increase risk of infections, hematologic adverse events, and malignancy. Not recommended for use with strong CYP3A4 inhibitors. Pregnancy category not established; adequate contraception recommended during treatment. Regular monitoring of blood counts recommended.
Official drug label
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy