Dexamethasone Sodium Phosphate
Dexamethasone Sodium Phosphate is a synthetic corticosteroid medication available in injectable and other forms that provides potent anti-inflammatory and immunosuppressant effects. It is used to treat a wide range of conditions including severe allergic reactions, inflammatory disorders, certain cancers, and conditions requiring reduction of immune system activity. This medication works by mimicking the effects of hormones naturally produced by the adrenal glands.
A potent corticosteroid used to reduce inflammation and suppress immune responses in various acute and chronic conditions.
Key facts at a glance
- RxNorm
- 48933
- Generic
- Dexamethasone Sodium Phosphate
- Class
- pin-variant
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treats severe allergic reactions, inflammatory conditions such as arthritis and inflammatory bowel disease, certain skin disorders, respiratory conditions like asthma exacerbations, adrenal insufficiency, and is used as part of chemotherapy regimens for certain cancers. It was also used in severe COVID-19 cases to reduce inflammation.
Works by binding to glucocorticoid receptors and influencing gene expression to reduce inflammation, decrease immune system activity, and inhibit the release of inflammatory mediators. It also affects carbohydrate, protein, and fat metabolism.
Long-term use requires gradual dose tapering to avoid adrenal insufficiency. May cause side effects including increased blood sugar, fluid retention, mood changes, and increased infection risk. Contraindicated in patients with systemic fungal infections. Use with caution in patients with diabetes, hypertension, or osteoporosis.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy