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Dexetimide Hydrochloride

Published: July 26, 2026Updated: August 25, 2026

Dexetimide Hydrochloride is an anticholinergic medication historically used to treat movement disorders. It was primarily prescribed for drug-induced parkinsonism and other extrapyramidal symptoms caused by antipsychotic medications.

Quick summary

An anticholinergic agent used to manage drug-induced movement disorders and parkinsonian symptoms.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 25, 2026Editorial policy

Key facts at a glance

RxNorm
259361
Generic
Dexetimide Hydrochloride
Class
pin-variant
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Dexetimide was used to treat extrapyramidal symptoms associated with antipsychotic medications, drug-induced parkinsonism, and other movement disorders. It has also been investigated for potential use in conditions involving cholinergic dysfunction.

As an anticholinergic agent, dexetimide blocks acetylcholine receptors in the central and peripheral nervous system. This helps restore the balance between dopamine and acetylcholine, which can become imbalanced in Parkinson's disease or when dopamine-blocking medications cause extrapyramidal side effects.

Due to its anticholinergic properties, common side effects may include dry mouth, blurred vision, constipation, urinary retention, and cognitive effects. It should be used with caution in elderly patients and those with glaucoma, urinary obstruction, or gastrointestinal conditions. This medication is no longer widely available in many countries.

Official drug label

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Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy