Dexpanthenol
Dexpanthenol is a provitamin B5 compound that converts to pantothenic acid in the body, supporting skin healing and repair processes. It is primarily used topically for wound healing and skin irritation.
Dexpanthenol is a topical and systemic vitamin B5 derivative used for wound healing, skin hydration, and treating various skin and mucous membrane conditions.
Key facts at a glance
- ATC
- A11HA30
- RxNorm
- 22701
- Generic
- Dexpanthenol
- Class
- atc-a11
- Brands
- Infuvite, Infuvite Pediatric, Ellis Tonic, Eldertonic
- Availability
- rx
- Lactation
- unknown
- Routes
- oral, topical
- Forms
- solution, tablet, ointment
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Dosage and administration
- Usual dose
- 500mg twice daily
- Maximum
- consult physician
- Frequency
- every 12 hours
- Instructions
- Follow physician instructions
- Duration limits
- as prescribed
- Monitoring
- standard
- Usual dose
- 250mg twice daily
- Maximum
- consult physician
- Frequency
- every 12 hours
- Instructions
- Follow physician instructions
- Duration limits
- as prescribed
- Monitoring
- standard
- Usual dose
- 400mg daily
- Maximum
- consult physician
- Frequency
- once daily
- Instructions
- Follow physician instructions
- Duration limits
- as prescribed
- Monitoring
- standard
Overdose information
Special Populations
9 groupspregnancy
first trimesteruse only if benefits outweigh risks
avoid oral formulations during first trimester unless specifically prescribed, topical application generally considered safer
regular prenatal monitoring
Use with caution and monitor for adverse effects.
pregnancy
second trimesteruse with caution
topical dexpanthenol cream may be used for skin care, oral supplements only if prescribed
routine prenatal checkups
Use with caution and monitor for adverse effects.
pregnancy
third trimesterno adjustment needed for topical use
topical application is generally considered safe for skin care
standard prenatal care
lactation
breastfeedingno adjustment needed
topical dexpanthenol is safe during breastfeeding; oral supplements should be discussed with healthcare provider
no specific monitoring required
geriatric
elderlyno specific adjustment required
suitable for elderly patients; monitor skin sensitivity with topical use
periodic skin assessment for topical users
pediatric_age
infantsuse under medical supervision
only use pediatric formulations as directed by physician; avoid adult formulations
monitor for skin irritation or allergic reactions
Use with caution and monitor for adverse effects.
pediatric_age
childrenuse age-appropriate formulations
topical dexpanthenol is generally safe for children; follow dosing guidelines for supplements
monitor for skin sensitivity
renal_impairment
mild to moderateno adjustment needed for topical use
topical application does not require dose adjustment; oral supplements use standard dosing
no specific monitoring required
hepatic_impairment
anyno adjustment needed
dexpanthenol is metabolized locally in skin; no hepatic dose adjustment required
no specific monitoring required
Statistics and clinical data
Drug class
Dexpanthenol is a provitamin of pantothenic acid used in topical formulations
Common uses
Topical application for skin conditions
Commonly prescribed since
Historical prescribing information for topical dexpanthenol products
Common formulations
Available pharmaceutical dosage forms
Topical dexpanthenol is used for minor wounds, burns, skin irritations, dry skin, and as a moisturizing agent. It may also be used for aftercare following laser treatments or superficial dermatological procedures. Oral formulations may be used for certain gastrointestinal conditions involving mucous membrane healing.
Dexpanthenol acts as a humectant that attracts and retains moisture in the skin. Once absorbed, it converts to pantothenic acid (vitamin B5), which plays a role in cellular metabolism and the synthesis of coenzyme A, supporting the skin's natural repair mechanisms and promoting epithelial cell regeneration.
Dexpanthenol is generally well-tolerated with minimal systemic absorption when applied topically. It is contraindicated in individuals with known hypersensitivity to the substance. Avoid application on actively infected wounds. As a vitamin derivative, drug interactions are uncommon, but consult a healthcare provider for specific medical advice.
Contraindications
Conditions and patient states where this medication should be avoided or used with caution.
Do not use (1)
Known allergy to this medication or its components
Use caution (1)
Consult healthcare provider for benefits vs risks assessment
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 24, 2026. · Read our editorial policy