Dexrazoxane Hydrochloride
Dexrazoxane Hydrochloride is a cardioprotective agent administered by injection to reduce the risk of heart damage associated with certain chemotherapy drugs, particularly anthracyclines like doxorubicin. It works by binding to iron and preventing the formation of harmful free radicals that can injure heart muscle cells during cancer treatment.
A cardioprotective injection used to prevent heart damage in patients receiving certain chemotherapy medications.
Key facts at a glance
- RxNorm
- 1294534
- Generic
- Dexrazoxane Hydrochloride
- Class
- pin-variant
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Prevention of anthracycline-induced cardiotoxicity (heart damage) in patients undergoing chemotherapy treatment, particularly those receiving doxorubicin or similar anthracycline antibiotics for cancer therapy.
Dexrazoxane is an iron chelating agent that works by binding free iron in tissues and preventing it from participating in the formation of reactive oxygen species (free radicals). This reduces oxidative stress on heart muscle cells during anthracycline chemotherapy.
Administered by intravenous injection, typically before anthracycline chemotherapy. May cause bone marrow suppression and other side effects. Does not prevent other chemotherapy-related toxicities. Use should be determined by a healthcare provider based on individual patient factors and treatment regimen.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy