Dextromethorphan Polistirex
Dextromethorphan Polistirex is an extended-release cough suppressant used to temporarily relieve coughs caused by minor throat and bronchial irritation. It works by acting on the cough center in the brain to reduce the urge to cough, providing relief for up to 12 hours per dose. This medication is available over-the-counter and is suitable for adults and children over a certain age.
An extended-release cough suppressant that reduces urge to cough by acting on the brain's cough center.
Key facts at a glance
- RxNorm
- 236146
- Generic
- Dextromethorphan Polistirex
- Class
- pin-variant
- Brands
- Delsym
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Temporarily relieves cough due to minor throat and bronchial irritation from colds, allergies, or inhaled irritants. Used for non-productive (dry) coughs.
Acts as a cough suppressant by affecting the cough center in the medulla oblongata of the brain, reducing the frequency and intensity of coughing without suppressing the body's natural ability to clear airways.
Extended-release formulation provides longer relief than standard dextromethorphan. Avoid use with MAO inhibitors. May cause drowsiness. Do not use for persistent coughs, coughs with excessive mucus, or coughs caused by smoking/asthma without medical advice. Keep out of reach of children.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 28, 2026. · Read our editorial policy