Dibucaine
Dibucaine is a potent local anesthetic agent belonging to the amide class, primarily used in topical formulations for the symptomatic relief of pain, itching, and discomfort associated with various conditions. It is commonly found in over-the-counter hemorrhoidal preparations and topical analgesic products for external use only.
Dibucaine is a topical local anesthetic used to relieve pain and itching from hemorrhoids and minor skin irritations.
Key facts at a glance
- ATC
- C05
- RxNorm
- unknown
- Generic
- Dibucaine
- Class
- atc-c05
- Brands
- Nupercainal
- Availability
- otc
- Pregnancy
- C
- Lactation
- caution
- Half-life (h)
- 0
- Onset (min)
- 5
- Duration (h)
- 2
- Routes
- rectal, topical
- Forms
- cream, ointment
- Regions
- United States, Canada, United Kingdom, Australia
- Monitoring
- skin irritation, allergic reactions
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Used for temporary relief of pain, itching, and discomfort from hemorrhoids (piles), minor burns, sunburn, insect bites, and skin irritations. Available in topical cream and ointment formulations for external use only.
Acts as a local anesthetic by blocking sodium channels in nerve fibers, thereby inhibiting the initiation and transmission of nerve impulses. This results in temporary numbness of the applied area.
For external use only; avoid contact with eyes and mucous membranes. Should not be used on large areas of broken skin or for extended periods. Not recommended for use in children without medical supervision. Systemic absorption may occur, particularly from damaged skin, and rare allergic reactions have been reported.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy