Dibucaine Hydrochloride
Dibucaine Hydrochloride is a potent amide-type local anesthetic that was historically used for topical, infiltration, and spinal anesthesia. Due to concerns about cardiotoxicity, it has largely been replaced by safer alternatives in clinical practice, though it may still be found in some topical formulations for temporary relief of pain and itching.
Dibucaine Hydrochloride is a potent local anesthetic that blocks nerve signals to relieve pain, though its use has declined due to safety concerns.
Key facts at a glance
- RxNorm
- 235402
- Generic
- Dibucaine Hydrochloride
- Class
- pin-variant
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Used for topical anesthesia of skin and mucous membranes, particularly for relief of pain and itching from hemorrhoids, minor burns, and skin irritations. Historically used for infiltration and spinal anesthesia but rarely used systemically today.
Blocks voltage-gated sodium channels in nerve fibers, preventing the generation and conduction of nerve impulses. This results in temporary loss of sensation in the area where it is applied or injected.
This medication carries significant risks including potential for serious cardiac arrhythmias and systemic toxicity. It should only be used under medical supervision. Not recommended for use in children or for extended areas of application. Topical preparations containing low concentrations are considered safer than injectable forms.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy