Dicloxacillin Sodium
Dicloxacillin Sodium is a penicillinase-resistant penicillin antibiotic used to treat bacterial infections caused by susceptible staphylococci and streptococci. It works by inhibiting bacterial cell wall synthesis, making it particularly effective against penicillin-resistant staph infections. This medication is typically prescribed for skin infections, wound infections, and other conditions where penicillin-resistant bacteria are suspected.
An antibiotic used to treat staph and other bacterial infections by preventing bacterial cell wall growth.
Key facts at a glance
- RxNorm
- 267257
- Generic
- Dicloxacillin Sodium
- Class
- pin-variant
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment of skin and soft tissue infections caused by penicillin-resistant staphylococci, as well as streptococcal infections including pneumonia, bronchitis, and other respiratory tract infections. Also used for infected wounds, abscesses, and bone infections.
Binds to penicillin-binding proteins (PBPs) on bacterial cell walls, inhibiting the transpeptidation step of peptidoglycan synthesis. This weakens the cell wall, causing osmotic lysis and bacterial death. Its penicillinase-resistant structure allows it to remain effective against bacteria that produce penicillinase enzymes.
Should not be used in patients with penicillin hypersensitivity due to risk of cross-reactivity. May cause gastrointestinal side effects like nausea and diarrhea. Full course must be completed as prescribed. May reduce effectiveness of oral contraceptives and interact with blood thinners. Report any signs of allergic reaction, severe diarrhea, or new infections during treatment.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy