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Dienogest

Published: July 26, 2026Updated: July 26, 2026

Dienogest is a synthetic progestogen used as a component in combined oral contraceptives and for the treatment of endometriosis. It prevents pregnancy primarily by suppressing ovulation and altering the endometrium to inhibit implantation.

Quick summary

A synthetic progestogen hormone used in hormonal contraceptives and endometriosis treatment that works by suppressing ovulation.

Medically reviewed by WellAlly Editorial TeamLast reviewed July 26, 2026Editorial policy
BOXED WARNING

This medication carries a boxed (black box) warning — the strongest type of FDA warning. Review the full prescribing information before use.

Key facts at a glance

ATC
G03DB08
RxNorm
22968
Generic
Dienogest
Class
atc-g03
Brands
—
Availability
rx
Lactation
unknown
Routes
oral
Forms
tablet
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Dienogest is used as the progestogen component in combined oral contraceptives and is indicated for the treatment of endometriosis. It may also be used in other hormonal preparations depending on the specific formulation and country.

As a selective progestogen receptor agonist, dienogest suppresses ovulation, thickens cervical mucus to impede sperm penetration, and causes atrophic changes in the endometrium that prevent implantation. It also exhibits mild anti-androgenic activity.

Like all hormonal contraceptives, dienogest does not protect against sexually transmitted infections. Contraindications may include thromboembolic disorders, liver disease, or hormone-sensitive conditions. Common side effects may include irregular uterine bleeding, headache, and mood changes. Use requires appropriate medical evaluation and ongoing supervision by a healthcare provider.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy