Skip to content

Diethylpropion Hydrochloride

Published: July 26, 2026Updated: August 28, 2026

Diethylpropion Hydrochloride is a prescription appetite suppressant used as a short-term adjunct in a weight management program for patients with obesity. It belongs to the sympathomimetic amine class of medications and works by reducing hunger sensations to help patients eat less.

Quick summary

A prescription appetite suppressant used short-term to aid weight loss in obesity when combined with diet and exercise.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 28, 2026Editorial policy

Key facts at a glance

RxNorm
81998
Generic
Diethylpropion Hydrochloride
Class
pin-variant
Brands
Tenuate
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Short-term weight management in patients with obesity (BMI ≥30) or overweight patients (BMI ≥27) with weight-related conditions such as hypertension, diabetes, or dyslipidemia, as part of a comprehensive treatment plan including diet and exercise.

Acts as a sympathomimetic amine that stimulates the central nervous system, primarily affecting the hypothalamus to reduce appetite and food intake. Its precise anorectic mechanism involves norepinephrine and dopamine reuptake inhibition.

For short-term use only (typically 12 weeks or less); not suitable for cosmetic weight loss. Contraindicated in patients with glaucoma, hyperthyroidism, and those with history of substance abuse. May cause insomnia, dry mouth, and increased heart rate. Use with caution in patients with cardiovascular disease or psychiatric conditions. Discontinue use if no weight loss occurs after 4 weeks.

Official drug label

WellAlly may earn a referral fee from linked resources at no extra cost to you. Editorial content is never influenced by commercial relationships.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 28, 2026. · Read our editorial policy