Adapalene
Differin (adapalene) is a topical retinoid medication used to treat acne vulgaris. It works by normalizing skin cell turnover and reducing inflammation to prevent pore blockages and lesions.
Differin is a topical acne treatment that helps clear and prevent pimples by normalizing skin cell turnover.
Key facts at a glance
- RxNorm
- 153184
- Generic
- Differin
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment of acne vulgaris (common acne) on the face, chest, back, and shoulders. It helps clear existing pimples and prevent new ones from forming.
Adapalene is a retinoid that binds to specific receptors in skin cells, normalizing cell differentiation and turnover. It reduces the formation of microcomedones (clogged pores) and has anti-inflammatory properties to reduce lesion development.
May cause skin dryness, redness, and peeling especially during the first few weeks. Use sunscreen daily as it increases sun sensitivity. Avoid using on broken, eczema-affected, or sunburned skin. Results typically appear after 8-12 weeks of consistent use. Consult a doctor before use if pregnant.
Official drug label
WellAlly may earn a referral fee from linked resources at no extra cost to you. Editorial content is never influenced by commercial relationships.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy