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Diflorasone Diacetate

Published: July 26, 2026Updated: August 25, 2026

Diflorasone Diacetate is a high-potency topical corticosteroid medication used to treat inflammatory and itchy skin conditions. It is typically prescribed for conditions such as eczema, psoriasis, and dermatitis when lower-potency steroids have not been effective. The medication is applied directly to the affected area of skin to reduce redness, swelling, and itching.

Quick summary

Diflorasone Diacetate is a topical corticosteroid cream or ointment that treats inflammatory skin conditions like eczema and psoriasis by reducing inflammation and itching.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 25, 2026Editorial policy

Key facts at a glance

RxNorm
23033
Generic
Diflorasone Diacetate
Class
pin-variant
Brands
Psorcon, Apexicon
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Diflorasone Diacetate is used to treat inflammatory skin conditions including atopic dermatitis, eczema, psoriasis, contact dermatitis, and other corticosteroid-responsive dermatoses. It is generally reserved for moderate to severe cases when milder corticosteroids have proven ineffective.

As a topical corticosteroid, diflorasone diacetate works by suppressing the immune response in the skin and reducing inflammation. It decreases the production of inflammatory chemicals and inhibits the migration of inflammatory cells to the affected area, thereby reducing redness, swelling, and itching.

Diflorasone Diacetate is for external use only and should not be applied to broken or infected skin unless directed by a physician. Use should be limited to the smallest effective amount and shortest duration possible to minimize side effects such as skin thinning, stretch marks, or systemic absorption. It should not be used on the face, groin, or armpits unless specifically prescribed. Patients should avoid covering treated areas with occlusive dressings unless instructed, as this increases absorption and risk of side effects.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy