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Diflucortolone

Published: July 26, 2026Updated: August 25, 2026

Diflucortolone is a potent topical corticosteroid used to treat inflammatory and itchy skin conditions. It works by reducing inflammation, swelling, and allergic reactions in the skin. This medication is typically prescribed for conditions such as eczema, dermatitis, and psoriasis.

Quick summary

Diflucortolone is a topical corticosteroid cream or ointment used to reduce inflammation and itching from various skin conditions.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 25, 2026Editorial policy

Key facts at a glance

ATC
D07AC06
RxNorm
3392
Generic
Diflucortolone
Class
atc-d07
Brands
—
Availability
rx
Lactation
unknown
Routes
topical
Forms
ointment, cream
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Diflucortolone is used to treat inflammatory and pruritic (itchy) skin disorders including atopic dermatitis, contact dermatitis, eczema, psoriasis, and other steroid-responsive dermatoses.

As a corticosteroid, diflucortolone works by suppressing the inflammatory response and reducing immune activity in the skin. It decreases the production of inflammatory substances and reduces the activity of immune cells, thereby alleviating redness, swelling, itching, and discomfort.

Diflucortolone is for external use only and should not be applied to broken skin, large areas of the body, or used for prolonged periods without medical supervision. It should be used with caution on the face and in children. Common side effects may include skin thinning, stretch marks, or local irritation with prolonged use.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy