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Dihydro-Beta-Ergocryptine Mesylate

Published: July 26, 2026Updated: August 25, 2026

Dihydroergocryptine mesylate is an ergot derivative with both dopamine agonist and alpha-adrenergic blocking properties. It is used primarily in the treatment of Parkinson's disease and peripheral vascular disorders, and may also be prescribed for age-related cognitive decline and migraine prevention in certain countries where it is approved.

Quick summary

An ergot-derived dopamine agonist used for movement disorders and vascular conditions.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 25, 2026Editorial policy

Key facts at a glance

RxNorm
1426905
Generic
Dihydro-Beta-Ergocryptine Mesylate
Class
pin-variant
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Primarily used for Parkinson's disease (often as adjunctive therapy), peripheral arterial circulation disorders, and may be used for vascular migraines and cognitive symptoms in some regions. Availability varies significantly by country.

Acts as a partial dopamine agonist at D2 receptors while also providing alpha-adrenergic blockade. This dual action helps improve dopaminergic transmission and reduce vascular tone, addressing both neurological and vascular components of treated conditions.

Not FDA-approved in the United States but available in Europe and other regions. Common side effects include nausea, dizziness, and orthostatic hypotension. Contraindicated in pregnancy, severe cardiovascular disease, and with other ergot derivatives. Regular monitoring of blood pressure recommended during treatment.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy