Dihydroergocryptine Mesylate
Dihydroergocryptine Mesylate is an ergot-derived dopamine agonist used primarily in the treatment of cognitive decline, including vascular dementia and age-related memory impairment, as well as peripheral circulation disorders. It acts on dopamine receptors and has vasodilatory properties that may improve cerebral blood flow. This medication is available in several European and international markets but is not currently approved by the FDA for use in the United States.
Dihydroergocryptine Mesylate is a dopamine agonist used for cognitive decline and circulation disorders, available internationally but not FDA-approved.
Key facts at a glance
- RxNorm
- 42646
- Generic
- Dihydroergocryptine Mesylate
- Class
- pin-variant
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Primarily used for symptomatic treatment of cognitive impairment and dementia, particularly vascular dementia. Also prescribed for peripheral circulatory disorders such as Raynaud's phenomenon and intermittent claudication.
Functions as a dopamine D2 receptor agonist with alpha-adrenergic blocking activity. This dual action helps improve cerebral blood flow, enhance dopaminergic transmission in the central nervous system, and may provide neuroprotective effects.
Available as oral formulations in many countries worldwide. Not approved by the FDA in the United States. Common side effects may include nausea, headache, and dizziness. Contraindicated in patients with cardiovascular disease, uncontrolled hypertension, or known ergot hypersensitivity. Should be used with caution in elderly patients and those with psychiatric disorders.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 28, 2026. · Read our editorial policy