Dihydroergotamine Tartrate
Dihydroergotamine Tartrate is an ergot alkaloid derivative used for the acute treatment of migraine headaches. It acts as a serotonin (5-HT1B/5-HT1D) receptor agonist and causes vasoconstriction of cranial blood vessels to relieve migraine symptoms. This medication is typically administered via injection, nasal spray, or orally.
Dihydroergotamine Tartrate is an ergot-derived medication used to treat acute migraine attacks by narrowing blood vessels in the brain and acting on serotonin receptors.
Key facts at a glance
- RxNorm
- 236680
- Generic
- Dihydroergotamine Tartrate
- Class
- pin-variant
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Acute treatment of migraine headaches with or without aura. It is not used for migraine prevention but rather for resolving active migraine attacks once they have begun.
Acts as an agonist at serotonin (5-HT1B and 5-HT1D) receptors in the brain and causes vasoconstriction of cranial blood vessels, which helps reverse the dilation associated with migraine attacks.
Should not be used by patients with cardiovascular disease, uncontrolled hypertension, or those taking other ergot derivatives or potent CYP3A4 inhibitors due to risk of severe vasoconstriction. Common side effects include nausea, vomiting, dizziness, and injection site reactions. Should only be used during a migraine attack and not prophylactically.
Official drug label
WellAlly may earn a referral fee from linked resources at no extra cost to you. Editorial content is never influenced by commercial relationships.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy