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Dimenhydrinate

Published: July 26, 2026Updated: August 25, 2026

Dimenhydrinate is an antihistamine medication primarily used to prevent and treat motion sickness, including symptoms of nausea, vomiting, and dizziness. It works by acting on the inner ear and brain to suppress signals that trigger these symptoms.

Quick summary

An antihistamine used to prevent and treat nausea, vomiting, and dizziness from motion sickness.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 25, 2026Editorial policy

Key facts at a glance

ATC
R06AA
RxNorm
unknown
Generic
Dimenhydrinate
Class
atc-r06
Brands
Wal-Dram, Airmit, Dramamine, Driminate, TripTone, Gravol
Availability
otc
Pregnancy
B
Lactation
caution
Half-life (h)
4
Onset (min)
30
Duration (h)
4
Routes
oral
Forms
tablet, chewable tablet, oral solution, liquid
Regions
worldwide
Monitoring
drowsiness, sedation, dry mouth

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Prevention and treatment of motion sickness, including nausea, vomiting, and vertigo associated with travel. May also be used for vertigo from other causes.

Acts as an H1 antihistamine and anticholinergic agent, blocking signals in the vomiting center of the brain and inner ear that trigger nausea and dizziness.

May cause drowsiness and should be used with caution when driving or operating machinery. Avoid alcohol and other sedating medications while taking this drug. Not recommended for premature infants or newborns. May interact with other anticholinergic medications. Consult a healthcare provider before use if pregnant, breastfeeding, or having certain conditions like glaucoma, urinary retention, or respiratory disorders.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy