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Dimethicone 100

Published: July 26, 2026Updated: August 25, 2026

Dimethicone 100 is a silicone-based topical medication that acts as an emollient and skin protectant. It creates a protective barrier on the skin surface and helps retain moisture, making it useful for various dermatological conditions. This medication is commonly used in both clinical and over-the-counter formulations.

Quick summary

Dimethicone 100 is a silicone-based skin protectant used to moisturize and shield the skin from irritants.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 25, 2026Editorial policy

Key facts at a glance

RxNorm
1310496
Generic
Dimethicone 100
Class
pin-variant
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Treats and prevents dry, chapped, or irritated skin; commonly used for diaper rash, minor burns, skin irritations, and as a protective barrier for sensitive or damaged skin.

Forms a hydrophobic (water-repellent) barrier on the skin surface that helps seal in moisture and protects against external irritants, while allowing the skin to breathe.

For external use only; avoid contact with eyes and open wounds; generally well-tolerated with minimal systemic absorption; discontinue use if irritation or allergic reaction occurs.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy