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Dimethindene Maleate

Published: July 26, 2026Updated: August 25, 2026

Dimethindene Maleate is a second-generation antihistamine used to treat allergic conditions such as hay fever, allergic rhinitis, itching, and urticaria (hives). It works by blocking histamine H1 receptors, reducing allergic symptoms like sneezing, runny nose, and skin irritation. This medication is available in oral and topical formulations.

Quick summary

Dimethindene Maleate is an antihistamine used to relieve allergy symptoms like itching, sneezing, and hives.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 25, 2026Editorial policy

Key facts at a glance

RxNorm
258334
Generic
Dimethindene Maleate
Class
pin-variant
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Treatment of seasonal and perennial allergic rhinitis, allergic conjunctivitis, itching and skin conditions such as urticaria (hives), eczema, and insect bites. Also used for symptomatic relief of cold symptoms in some formulations.

It is a selective H1-antihistamine that competitively blocks histamine H1 receptors, preventing histamine from triggering allergic inflammatory responses. This reduces symptoms like itching, swelling, and mucus production.

May cause drowsiness in some individuals (though considered a non-sedating antihistamine). Avoid alcohol and CNS depressants while taking this medication. Consult a healthcare provider before use if pregnant, breastfeeding, or taking other medications. Topical use should be avoided on broken or inflamed skin.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy