Dinoprost Tromethamine
Dinoprost Tromethamine is a synthetic prostaglandin F2α analog that stimulates uterine smooth muscle contraction. It is primarily used in obstetrics and gynecology for labor induction, treatment of missed abortion, and management of postpartum hemorrhage. The medication works by binding to prostaglandin receptors in the uterus, causing powerful contractions that help evacuate the uterine contents.
Dinoprost Tromethamine is a prostaglandin F2α analog used to induce uterine contractions for labor induction, abortion treatment, and postpartum bleeding control.
Key facts at a glance
- RxNorm
- 23321
- Generic
- Dinoprost Tromethamine
- Class
- pin-variant
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Used for labor induction at term, treatment of missed abortion or intrauterine fetal demise during the second trimester, and management of postpartum hemorrhage when other measures fail. In veterinary medicine, it is used for similar reproductive indications in animals.
Dinoprost is a synthetic analog of prostaglandin F2α that binds to FP receptors in uterine smooth muscle, triggering powerful contractions. It also promotes luteolysis (breakdown of the corpus luteum) by acting on CL receptors in the ovaries, reducing progesterone production which supports its abortifacient effects.
Contraindicated in patients with active asthma, glaucoma, or uterine surgery history. Must be administered under close medical supervision with fetal and uterine monitoring during labor induction. Can cause bronchoconstriction and increased intraocular pressure. Not for unmonitored outpatient use.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 28, 2026. · Read our editorial policy