Diosmin
Diosmin is a flavonoid medication used primarily for the treatment of chronic venous insufficiency and related circulatory disorders. It is commonly prescribed for symptoms such as heavy legs, leg pain, swelling, and hemorrhoids. The medication is available in oral tablet form and is often used as a phlebotonic agent.
Diosmin is a venous-protective medication used to treat chronic venous insufficiency, hemorrhoids, and related circulatory symptoms.
Key facts at a glance
- ATC
- C05CA03
- RxNorm
- 3489
- Generic
- Diosmin
- Class
- atc-c05
- Brands
- Vasoflex D1
- Availability
- rx
- Lactation
- unknown
- Routes
- oral
- Forms
- tablet
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Diosmin is used to treat chronic venous diseases including chronic venous insufficiency, varicose veins, heavy legs, leg pain, and edema. It is also used for symptomatic relief of acute hemorrhoidal attacks and is sometimes used in phlebitis and post-surgical treatment of varicose veins.
Diosmin works by improving venous tone and reducing venous capacitance and distensibility. It enhances lymphatic drainage and reduces capillary hyperpermeability. The medication also has anti-inflammatory and antioxidant properties that help reduce edema and improve microcirculation.
Diosmin is generally well-tolerated with mild side effects including gastrointestinal disturbances. It is typically used in combination with hesperidin (a related flavonoid). Safety in pregnancy and breastfeeding is not fully established, so consultation with a healthcare provider is recommended before use.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy