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Diphenidol Hydrochloride

Published: July 26, 2026Updated: August 25, 2026

Diphenidol Hydrochloride is an antiemetic and antivertigo agent primarily used to prevent and treat nausea, vomiting, and vertigo associated with conditions such as Meniere's disease, labyrinthitis, and motion sickness. It acts on the vestibular system to reduce symptoms of dizziness and imbalance.

Quick summary

Diphenidol Hydrochloride is an antiemetic medication used to treat nausea, vomiting, and vertigo.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 25, 2026Editorial policy

Key facts at a glance

RxNorm
47877
Generic
Diphenidol Hydrochloride
Class
pin-variant
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Used to prevent and treat nausea, vomiting, and vertigo associated with vestibular disorders such as Meniere's disease, labyrinthitis, and motion sickness. May also be used for postoperative nausea and vomiting.

Exerts antiemetic and antivertigo effects through anticholinergic activity in the vestibular system and possibly antihistamine properties. It helps normalize vestibular function and reduces signals that trigger nausea and vomiting.

May cause drowsiness, dry mouth, blurred vision, and urinary retention. Use with caution in patients with glaucoma, urinary retention, or benign prostatic hyperplasia. Not recommended for use in pregnant women unless clearly needed. Alcohol may enhance sedative effects.

Official drug label

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Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy