Dipivefrin
Dipivefrin is an ophthalmic prodrug medication that is converted to epinephrine in the eye. It is primarily used to lower intraocular pressure in patients with glaucoma or ocular hypertension. The medication is applied topically as eye drops and serves as an alternative to direct epinephrine administration.
Dipivefrin is an eye drop medication used to reduce eye pressure in glaucoma patients by converting to epinephrine upon application.
Key facts at a glance
- ATC
- S01EA02
- RxNorm
- 23410
- Generic
- Dipivefrin
- Class
- atc-s01
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- ophthalmic
- Forms
- solution
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Dipivefrin is used to treat open-angle glaucoma and ocular hypertension. It may be prescribed when other glaucoma medications are not tolerated or are insufficient to control intraocular pressure.
As a prodrug, dipivefrin penetrates the cornea and is hydrolyzed to epinephrine. It then reduces aqueous humor production and increases outflow through the trabecular meshwork, thereby lowering intraocular pressure.
Common side effects may include eye stinging, redness, and pupil dilation. Patients with narrow-angle glaucoma, cardiovascular conditions, or hyperthyroidism should use this medication with caution. Contact lenses should be removed before administration and wait at least 15 minutes before reinserting.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy