Dipivefrin Hydrochloride
Dipivefrin Hydrochloride is an ophthalmic prodrug medication used to reduce elevated intraocular pressure in the treatment of glaucoma and ocular hypertension. It is a prodrug form of epinephrine that is converted to its active form within the eye, where it works by decreasing aqueous humor production and increasing uveoscleral outflow.
An ophthalmic prodrug of epinephrine used as an eye drop to lower eye pressure in glaucoma patients.
Key facts at a glance
- RxNorm
- 203156
- Generic
- Dipivefrin Hydrochloride
- Class
- pin-variant
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Primarily used to treat open-angle glaucoma and ocular hypertension. May also be used in other forms of glaucoma as adjunctive therapy.
As a prodrug, dipivefrin is converted to epinephrine in the eye by enzymatic hydrolysis. Epinephrine then reduces intraocular pressure by decreasing aqueous humor production and increasing uveoscleral outflow.
May cause eye irritation, blurred vision, or pupil dilation. Contraindicated in patients with narrow-angle glaucoma. Patients should wait several minutes between applying different eye medications if using multiple drops.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy