Dipotassium Glycyrrhizinate
Dipotassium Glycyrrhizinate is a potassium salt derivative of glycyrrhizinic acid, extracted from licorice root (Glycyrrhiza glabra). It is primarily used in topical formulations for its anti-inflammatory, anti-allergic, and skin-soothing properties. This agent is commonly employed in the management of various dermatological conditions characterized by inflammation, itching, or allergic skin reactions.
A topical anti-inflammatory and skin-soothing agent derived from licorice root, used for inflammatory and allergic skin conditions.
Key facts at a glance
- RxNorm
- 1367264
- Generic
- Dipotassium Glycyrrhizinate
- Class
- pin-variant
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Topical treatment of inflammatory and allergic skin conditions including dermatitis, eczema, pruritus (itching), and skin irritation. Also used in cosmetic and skincare products for its calming properties on sensitive or reactive skin.
Exerts anti-inflammatory effects by inhibiting lipid peroxidation and reducing the activity of inflammatory mediators. Demonstrates anti-allergic properties by stabilizing cell membranes and reducing histamine release. Provides skin-soothing benefits through its mild corticosteroid-like activity without the associated side effects.
Generally well-tolerated when applied topically with minimal systemic absorption. Avoid contact with eyes and mucous membranes. Patch testing recommended for individuals with known sensitivity to licorice-derived compounds. Not intended for oral consumption unless specifically formulated. Safety during pregnancy and breastfeeding not fully established; consult healthcare provider before use.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 28, 2026. · Read our editorial policy