Disopyramide Phosphate
Disopyramide Phosphate is a Class Ia antiarrhythmic medication used to treat and prevent certain types of irregular heartbeats, particularly ventricular arrhythmias. It works by blocking sodium channels in the heart, which slows electrical conduction and helps maintain normal heart rhythm. This medication is typically prescribed when other antiarrhythmic drugs are not suitable or have been ineffective.
Disopyramide Phosphate is an antiarrhythmic drug used to treat and prevent irregular heartbeats by blocking sodium channels in cardiac tissue.
Key facts at a glance
- RxNorm
- 203178
- Generic
- Disopyramide Phosphate
- Class
- pin-variant
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment and prevention of ventricular arrhythmias, including ventricular tachycardia and premature ventricular contractions. It may also be used for certain supraventricular arrhythmias when other medications are not appropriate.
Disopyramide is a Class Ia antiarrhythmic that blocks sodium channels in cardiac myocytes. This slows the rate of electrical impulse conduction, prolongs the action potential duration, and increases the effective refractory period, helping to stabilize irregular heart rhythms.
This medication can cause significant anticholinergic side effects including dry mouth, urinary retention, and blurred vision. It may worsen heart failure in some patients and can lower blood pressure excessively. Regular monitoring of ECG, blood pressure, and heart function is required. Disopyramide should not be stopped abruptly. Patients with certain heart conditions or glaucoma may need special consideration before use.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 28, 2026. · Read our editorial policy