Dolasetron
Dolasetron is an antiemetic medication that helps prevent and control nausea and vomiting, primarily used in patients undergoing chemotherapy or surgical procedures.
Dolasetron is an anti-nausea medication used to prevent chemotherapy-induced and postoperative nausea and vomiting.
Key facts at a glance
- ATC
- A04AA04
- RxNorm
- 68091
- Generic
- Dolasetron
- Class
- atc-a04
- Brands
- Anzemet
- Availability
- rx
- Lactation
- unknown
- Routes
- oral
- Forms
- tablet
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Prevention of nausea and vomiting associated with chemotherapy (including initial and repeat courses); prevention of postoperative nausea and vomiting in adults and pediatric patients.
Dolasetron is a selective 5-hydroxytryptamine-3 (5-HT3) receptor antagonist. It works by blocking serotonin (5-HT3) receptors in the chemoreceptor trigger zone and gastrointestinal tract, which helps prevent the activation of the vomiting reflex.
Dolasetron is available in oral and injectable formulations. Common side effects include headache, dizziness, and constipation. Cardiac effects (such as QT prolongation) have been reported, so caution is advised in patients with underlying heart conditions or electrolyte abnormalities. The injectable form is typically administered before the end of surgery.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy