Diflunisal
Dolobid (diflunisal) is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve pain, inflammation, and stiffness caused by conditions such as osteoarthritis and rheumatoid arthritis. It is also prescribed for the management of mild to moderate pain, including headache and dental pain. As a prescription-only brand-name medication, it works by reducing substances in the body that cause pain and inflammation.
Dolobid is an NSAID prescription medication used to treat pain and inflammation associated with arthritis and other conditions.
Key facts at a glance
- RxNorm
- 202486
- Generic
- Dolobid
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Dolobid is indicated for the treatment of osteoarthritis, rheumatoid arthritis, and mild to moderate pain conditions. It may also be used for pain relief following dental procedures or other surgical interventions.
As an NSAID, Dolobid works by inhibiting cyclooxygenase (COX) enzymes, which reduces the production of prostaglandins—chemicals in the body that promote inflammation, pain, and fever.
NSAIDs like Dolobid may increase the risk of serious cardiovascular events, gastrointestinal bleeding, and kidney damage. It should be used with caution in patients with a history of ulcers, heart disease, or kidney problems. Avoid using with other NSAIDs or blood thinners unless directed by a physician. Common side effects include stomach upset, nausea, and dizziness.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy