Doxapram
Doxapram is a respiratory stimulant that works by activating peripheral chemoreceptors in the carotid bodies to increase respiratory drive and improve alveolar ventilation. It is primarily used in hospital settings to treat respiratory depression following surgery or anesthesia, and may be used as a temporary measure in patients with acute respiratory insufficiency.
Doxapram is a respiratory stimulant used to treat breathing difficulties in hospitalized patients.
Key facts at a glance
- ATC
- R07AB01
- RxNorm
- 3637
- Generic
- Doxapram
- Class
- atc-r07
- Brands
- Dopram
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- solution
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment of respiratory depression following anesthesia or surgery, acute respiratory insufficiency, and as an adjunct in COPD patients with hypercapnia when other therapies are inadequate.
Stimulates peripheral chemoreceptors in the carotid bodies, leading to increased respiratory drive, improved tidal volume, and enhanced alveolar ventilation.
Administered intravenously in controlled hospital settings with close monitoring. Contraindicated in patients with severe coronary artery disease, uncontrolled hypertension, or epilepsy. May cause side effects including tachycardia, hypertension, or restlessness. Not a substitute for mechanical ventilation when indicated.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy