Doxapram Hydrochloride
Doxapram Hydrochloride is a respiratory stimulant that works by activating chemoreceptors in the carotid body to increase respiratory drive. It is primarily used in hospital settings to treat respiratory depression and to help wean patients from mechanical ventilation.
A respiratory stimulant used to treat respiratory depression and support breathing in acute care settings.
Key facts at a glance
- RxNorm
- 82011
- Generic
- Doxapram Hydrochloride
- Class
- pin-variant
- Brands
- Dopram
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Management of respiratory depression in post-operative patients, drug-induced respiratory depression, acute respiratory insufficiency associated with COPD exacerbations, and as an aid in weaning from mechanical ventilation.
Acts as a selective respiratory stimulant by exciting chemoreceptors in the carotid body, which triggers increased breathing rate and depth through direct stimulation of the respiratory center in the brainstem.
Must be administered in a monitored hospital setting due to risk of seizures, arrhythmias, and elevated blood pressure. Contraindicated in severe hypertension, coronary artery disease, and epilepsy. Should not be used as a substitute for mechanical ventilation in severe respiratory failure.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 28, 2026. · Read our editorial policy