Doxazosin Mesylate
Doxazosin Mesylate is an alpha-1 adrenergic blocker used to treat high blood pressure (hypertension) and symptoms of benign prostatic hyperplasia (BPH), a condition involving enlargement of the prostate gland. The medication works by relaxing blood vessels and smooth muscle in the prostate and bladder neck, improving blood flow and making urination easier.
Doxazosin Mesylate is an alpha-blocker that treats high blood pressure and benign prostatic hyperplasia (BPH) by relaxing smooth muscle in blood vessels and the urinary tract.
Key facts at a glance
- RxNorm
- 39173
- Generic
- Doxazosin Mesylate
- Class
- pin-variant
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Doxazosin Mesylate is primarily used to treat hypertension and benign prostatic hyperplasia (BPH). For BPH, it helps relieve urinary symptoms such as difficulty urinating, weak stream, and frequent urination.
As an alpha-1 adrenergic blocker, Doxazosin inhibits alpha-1 receptors on smooth muscle cells. This causes relaxation of smooth muscle in blood vessels (leading to vasodilation and reduced blood pressure) and in the prostate and bladder neck (improving urine flow).
Common side effects include dizziness, headache, and fatigue. A 'first-dose effect' may cause significant orthostatic hypotension, so the medication is often started at low doses. Patients should rise slowly from sitting or lying positions. Doxazosin is typically taken once daily and may interact with other blood pressure medications or PDE5 inhibitors.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 28, 2026. · Read our editorial policy