Oxymetazoline
Dristan 12-Hour Nasal Spray is a topical nasal decongestant spray designed to provide temporary relief from nasal congestion due to allergies, colds, or sinus irritation. The spray works by constricting blood vessels in the nasal passages, reducing swelling and stuffiness for up to 12 hours per dose.
Dristan 12-Hour Nasal Spray is an over-the-counter nasal decongestant that temporarily relieves stuffy nose symptoms for 12 hours per dose.
Key facts at a glance
- RxNorm
- 702024
- Generic
- Dristan 12-Hour Nasal Spray
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Provides temporary relief of nasal congestion caused by seasonal allergies, the common cold, sinusitis, or other upper respiratory allergies. It helps relieve stuffy nose, sinus pressure, and nasal discomfort associated with these conditions.
Contains oxymetazoline, an alpha-adrenergic agonist that works as a vasoconstrictor. When applied topically to the nasal passages, it narrows the blood vessels in the nasal lining, which reduces swelling and congestion, allowing for easier breathing.
For topical nasal use only. Should not be used for more than 3 consecutive days to avoid rebound congestion (rhinitis medicamentosa). Avoid contact with eyes. Not recommended for use by children under 6 years old without medical advice. Consult a healthcare provider if symptoms persist beyond 3 days or worsen.
Official drug label
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy