Dronabinol
Dronabinol is a synthetic form of tetrahydrocannabinol (THC) used as an antiemetic for patients experiencing nausea and vomiting from cancer chemotherapy and to stimulate appetite.
Dronabinol is a cannabinoid medication used to treat chemotherapy-induced nausea and AIDS-related appetite loss.
Key facts at a glance
- ATC
- A04AD10
- RxNorm
- 10402
- Generic
- Dronabinol
- Class
- atc-a04
- Brands
- Syndros, Marinol
- Availability
- rx
- Lactation
- unknown
- Routes
- oral
- Forms
- capsule, solution
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Dronabinol is FDA-approved for treating nausea and vomiting associated with cancer chemotherapy in patients who have not responded adequately to conventional antiemetic therapies. It is also indicated for the treatment of anorexia associated with weight loss in patients with AIDS.
Dronabinol acts on the body's endocannabinoid system by binding to cannabinoid receptors (CB1 and CB2) found in neural tissues throughout the central nervous system. This interaction produces complex effects on the CNS, including central sympathomimetic activity, which helps reduce nausea and vomiting and stimulates appetite.
Dronabinol is an oral medication and should be taken exactly as prescribed by a healthcare provider. Patients may experience side effects such as dizziness, euphoria, paranoia, or dry mouth. It may cause psychiatric effects and should be used with caution in patients with a history of substance use or mental health conditions. Driving and operating machinery should be avoided until the patient knows how the medication affects them.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy