Aluminum Chloride
Drysol is a prescription-strength topical antiperspirant used to treat excessive sweating (hyperhidrosis) affecting the underarms, hands, and feet. It contains aluminum chloride, which works by forming a gel-like barrier in the sweat ducts to reduce perspiration. This medication is typically recommended when regular over-the-counter antiperspirants have proven ineffective.
Drysol is a prescription-strength antiperspirant that treats excessive sweating by blocking sweat ducts.
Key facts at a glance
- RxNorm
- 92529
- Generic
- Drysol
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Drysol is indicated for the treatment of hyperhidrosis (excessive sweating), particularly affecting the axillary (underarm) region, palms of the hands, and soles of the feet when standard antiperspirants fail to provide adequate relief.
The active ingredient, aluminum chloride, penetrates the sweat ducts and reacts with skin proteins to form a mechanical plug that reduces sweat output. When applied at night to dry skin, it temporarily blocks the eccrine sweat glands to minimize perspiration.
Apply only to dry skin at night; allow to dry completely before dressing. Wash off the next morning. May cause skin irritation, burning, or itching. Avoid contact with eyes and broken skin. Do not use immediately after shaving. Consult a healthcare provider if pregnant or breastfeeding.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy