Halobetasol Propionate and Tazarotene
Duobrii is a topical combination medication containing a corticosteroid (halobetasol propionate) and a retinoid (tazarotene). It is prescribed for the treatment of plaque psoriasis in adults. The two active ingredients work together to reduce inflammation and normalize skin cell growth.
Duobrii is a topical combination medication used to treat plaque psoriasis by reducing inflammation and normalizing skin cell turnover.
Key facts at a glance
- RxNorm
- 2166090
- Generic
- Duobrii
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Duobrii is indicated for the topical treatment of plaque psoriasis in adult patients.
The medication combines halobetasol propionate, a potent corticosteroid that reduces inflammation and suppresses immune responses, with tazarotene, a retinoid that helps normalize skin cell differentiation and turnover.
Duobrii is for topical use only and should not be applied to the face, groin, or axillae. As a combination product containing a potent steroid, it carries risks of local and systemic side effects associated with corticosteroids. Patients should use the lowest effective strength for the shortest duration as directed by their healthcare provider. Pregnancy should be avoided due to the retinoid component.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy