Clonidine
Duraclon is the brand name for clonidine hydrochloride, an alpha-2 adrenergic agonist medication. It is primarily administered via epidural injection for the management of severe pain in cancer patients when other analgesics are insufficient. Duraclon works by reducing pain signal transmission in the nervous system through its action on alpha-2 receptors in the spinal cord.
Duraclon is an epidural pain medication used to manage severe cancer pain when other analgesics are inadequate.
Key facts at a glance
- RxNorm
- 216778
- Generic
- Duraclon
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Management of severe pain in cancer patients that is not adequately controlled with conventional analgesics, administered via epidural route.
As an alpha-2 adrenergic agonist, Duraclon acts on alpha-2 receptors in the spinal cord to reduce the transmission of pain signals, providing analgesic effects.
Must be administered only by or under the supervision of qualified medical professionals. May cause side effects including hypotension, dry mouth, drowsiness, and rebound hypertension if discontinued abruptly. Contraindicated in patients with certain cardiovascular conditions. Regular monitoring of blood pressure and other parameters is required during treatment.
Official drug label
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy