Triamterene
Dyrenium (triamterene) is a potassium-sparing diuretic that helps the body remove excess fluid while preserving potassium levels. It is typically prescribed to treat edema (fluid retention) associated with conditions such as heart failure, liver cirrhosis, or kidney disorders. This medication is often used when other diuretics are insufficient or need to be combined with potassium-wasting diuretics.
Dyrenium is a potassium-sparing diuretic used to treat fluid retention while preventing potassium loss.
Key facts at a glance
- RxNorm
- 203238
- Generic
- Dyrenium
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment of edema associated with heart failure, cirrhosis, and nephrotic syndrome. May be used alone or in combination with other diuretics to reduce potassium loss.
Triamterene works in the distal nephron of the kidneys by blocking epithelial sodium channels (ENaC), which reduces sodium reabsorption and subsequently decreases water reabsorption. This action prevents potassium excretion, helping maintain normal potassium levels while promoting fluid loss.
Regular monitoring of potassium levels is essential as hyperkalemia may occur. Use with caution in patients with kidney impairment. Avoid potassium supplements and potassium-rich foods unless directed. May interact with other medications including ACE inhibitors and ARBs. Common side effects include headache, nausea, and dizziness.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 28, 2026. · Read our editorial policy