Ebglyss
Ebglyss (lebrikizumab) is a prescription biologic medication used to treat moderate-to-severe atopic dermatitis (eczema) in adults and adolescents. It is an injectable monoclonal antibody that targets and inhibits interleukin-13 (IL-13), a key protein involved in the inflammatory process of eczema. Ebglyss is typically used when other treatments have not been effective or are not recommended.
Ebglyss is an injectable biologic medication for moderate-to-severe atopic dermatitis that works by blocking the IL-13 inflammatory protein.
Key facts at a glance
- RxNorm
- 2693786
- Generic
- Ebglyss
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Ebglyss is indicated for the treatment of moderate-to-severe atopic dermatitis in adults and adolescents aged 12 years and older who do not respond well to or cannot use other topical treatments.
Ebglyss is a monoclonal antibody that specifically binds to interleukin-13 (IL-13), a cytokine that plays a central role in the inflammation and symptoms of atopic dermatitis. By blocking IL-13, it helps reduce skin inflammation, itching, and other eczema symptoms.
Ebglyss is administered as a subcutaneous injection, typically every 4 weeks after an initial loading period. Common side effects may include injection site reactions and conjunctivitis. Patients should be monitored for signs of infection, as immunosuppressant medications may increase infection risk. Ebglyss should not be used in combination with other immunosuppressant biologics.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 31, 2026. · Read our editorial policy