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Azilsartan and Chlorthalidone

Published: July 26, 2026Updated: September 1, 2026

Edarbyclor is a brand-name combination medication used to treat high blood pressure (hypertension) in adults. It contains two active ingredients that work together: azilsartan, an angiotensin II receptor blocker (ARB) that helps relax blood vessels, and chlorthalidone, a thiazide-like diuretic that helps reduce fluid volume in the body. This combination approach helps lower blood pressure more effectively than either component alone.

Quick summary

Edarbyclor is a prescription blood pressure medication combining an ARB and diuretic to treat hypertension.

Medically reviewed by WellAlly Editorial TeamLast reviewed September 1, 2026Editorial policy

Key facts at a glance

RxNorm
1372759
Generic
Edarbyclor
Class
brand-name
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Edarbyclor is indicated for the treatment of hypertension in adults to lower blood pressure. It may be used as initial therapy for patients who need combination treatment or as a substitute for separately administered components.

Edarbyclor combines two complementary mechanisms: azilsartan blocks angiotensin II receptors, preventing blood vessel constriction, while chlorthalidone increases urine production to reduce fluid volume. Together, these actions decrease the workload on the heart and lower blood pressure.

Edarbyclor may cause dizziness or lightheadedness, especially during initial treatment. Patients should avoid alcohol and standing up quickly. It is contraindicated in pregnancy and should be used cautiously in patients with kidney or liver impairment. Regular blood pressure monitoring is recommended during treatment.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed September 1, 2026. · Read our editorial policy