Efavirenz
Efavirenz is an antiretroviral medication used in combination with other HIV medicines to treat HIV-1 infection. As a non-nucleoside reverse transcriptase inhibitor (NNRTI), it helps reduce the amount of HIV in the blood and may improve immune function.
Efavirenz is an HIV antiviral used in combination therapy to suppress HIV replication and slow disease progression.
Key facts at a glance
- ATC
- J05AG03
- RxNorm
- 195085
- Generic
- Efavirenz
- Class
- atc-j05
- Brands
- Symfi, Atripla
- Availability
- rx
- Lactation
- unknown
- Routes
- oral
- Forms
- capsule, tablet, solution
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Efavirenz is indicated for the treatment of HIV-1 infection in adults and children, used in combination with other antiretroviral agents. It is not a cure for HIV but helps control the infection.
Efavirenz is a non-nucleoside reverse transcriptase inhibitor (NNRTI) that binds directly to the reverse transcriptase enzyme of HIV-1, blocking the conversion of viral RNA into DNA. This prevents viral replication and reduces the spread of the virus.
Efavirenz should always be used as part of combination therapy, never as monotherapy. Common side effects include central nervous system symptoms such as vivid dreams, dizziness, and difficulty sleeping, especially when starting treatment. It should be taken on an empty stomach at bedtime to minimize side effects. Women of childbearing potential should use effective contraception due to potential fetal harm.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy