Efinaconazole
Efinaconazole is a topical azole antifungal medication used to treat onychomycosis, a fungal infection of the nails. It is applied directly to the affected nails and surrounding skin as a prescription solution. This medication works by inhibiting the growth of fungi responsible for the infection.
Efinaconazole is a prescription topical antifungal used to treat fungal nail infections.
Key facts at a glance
- ATC
- D01AC19
- RxNorm
- 1539753
- Generic
- Efinaconazole
- Class
- atc-d01
- Brands
- Jublia
- Availability
- rx
- Lactation
- unknown
- Routes
- topical
- Forms
- solution
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Efinaconazole is indicated for the topical treatment of onychomycosis (fungal infection of the nails) caused by dermatophytes such as Trichophyton rubrum and Trichophyton mentagrophytes. It is approved for use in adults.
As an azole antifungal, efinaconazole works by inhibiting the enzyme lanosterol 14-alpha-demethylase, which is essential for fungal cell membrane synthesis. By disrupting this process, the medication prevents fungal growth and replication.
Efinaconazole is for topical use only and should be applied exactly as directed by a healthcare provider. Avoid contact with eyes and mucous membranes. Patients should inform their doctor of any allergies or other medications being used, as drug interactions are generally minimal with topical administration.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy