Tesamorelin
Egrifta (tesamorelin) is a synthetic growth hormone-releasing factor analog used to reduce excess abdominal fat in HIV-infected patients with lipodystrophy. Administered as a daily subcutaneous injection, it works by stimulating the pituitary gland to produce and release endogenous growth hormone, which helps reduce visceral fat accumulation.
Egrifta is a brand-name injection medication used to treat excess abdominal fat in HIV patients with lipodystrophy by stimulating natural growth hormone production.
Key facts at a glance
- RxNorm
- 1044588
- Generic
- Egrifta
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Egrifta is indicated for the reduction of excess abdominal fat (visceral adipose tissue) in HIV-infected patients with lipodystrophy, a condition characterized by abnormal distribution of body fat often associated with antiretroviral therapy.
Egrifta contains tesamorelin, a synthetic analog of growth hormone-releasing hormone (GHRH). It binds to and stimulates GHRH receptors in the pituitary gland, promoting the synthesis and release of endogenous growth hormone, which subsequently helps reduce visceral fat accumulation.
Egrifta is administered as a daily subcutaneous injection. Common side effects may include injection site reactions, joint pain, and muscle aches. Patients should be monitored for elevated blood glucose levels and potential effects on pituitary function. Treatment should be discontinued if no improvement in visceral fat is observed after 12-16 weeks.
Official drug label
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy