Amitriptyline
Elavil (amitriptyline) is a tricyclic antidepressant used to treat major depressive disorder and certain types of chronic pain conditions. It works by increasing levels of serotonin and norepinephrine in the brain to help regulate mood and pain signals. This medication is available only as a brand-name product and is typically prescribed when other antidepressants have not been effective.
Elavil is a tricyclic antidepressant used for depression and chronic pain conditions.
Key facts at a glance
- RxNorm
- 42940
- Generic
- Elavil
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment of major depressive disorder, neuropathic pain, migraine prevention, and certain anxiety disorders. Sometimes used off-label for insomnia and fibromyalgia.
Inhibits the reuptake of serotonin and norepinephrine in the brain, increasing their availability to improve mood. Also has anticholinergic and antihistamine properties.
May cause drowsiness, dry mouth, weight gain, and constipation. Can increase suicidal risk in young adults under 25. Avoid alcohol and inform your doctor of any heart conditions before use. Requires gradual dose tapering when discontinuing.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy