Pegzilarginase
Elfabrio is a prescription medication used for enzyme replacement therapy in adults with confirmed Fabry disease. It works by providing an exogenous form of the enzyme alpha-galactosidase A, which is deficient in patients with this rare genetic disorder. This treatment helps reduce the accumulation of globotriaosylceramide (Gb3) in cells throughout the body.
Elfabrio is an enzyme replacement therapy for adults with Fabry disease that helps replenish deficient alpha-galactosidase A enzyme.
Key facts at a glance
- RxNorm
- 2637458
- Generic
- Elfabrio
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Elfabrio is indicated for the treatment of Fabry disease in adults with confirmed diagnosis of this rare lysosomal storage disorder caused by deficiency of the alpha-galactosidase A enzyme.
Elfabrio is a recombinant human alpha-galactosidase A enzyme that replaces the deficient or absent enzyme in patients with Fabry disease, helping to break down and reduce the accumulation of globotriaosylceramide (Gb3) in various tissues and organs.
Elfabrio is administered via intravenous infusion. Patients should be monitored for infusion-related reactions during treatment. As with other enzyme replacement therapies, hypersensitivity reactions may occur. Treatment should be overseen by physicians experienced in managing Fabry disease.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy