Pentosan Polysulfate Sodium
Elmiron (pentosan polysulfate sodium) is the only FDA-approved oral medication specifically for treating the bladder pain and discomfort associated with interstitial cystitis (IC), a chronic condition also known as painful bladder syndrome. It is typically used when other treatments have not provided adequate relief.
Elmiron is a brand-name medication approved to treat bladder pain and discomfort from interstitial cystitis.
Key facts at a glance
- RxNorm
- 155043
- Generic
- Elmiron
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Elmiron is prescribed for the treatment of interstitial cystitis (IC)/painful bladder syndrome, a chronic condition characterized by bladder pressure, bladder pain, pelvic discomfort, and urinary frequency or urgency.
The exact mechanism is not fully understood, but Elmiron is believed to work by adhering to and protecting the bladder lining (urothelium), potentially replenishing deficient glycosaminoglycans that help shield the bladder wall from irritating substances in the urine.
Elmiron has mild anticoagulant (blood-thinning) properties and may increase bleeding risk, especially when combined with other anticoagulants or before surgery. Long-term use has been associated with potential eye problems, including pigmentary maculopathy, so regular ophthalmologic monitoring is recommended. Common side effects include hair loss, diarrhea, nausea, and abdominal pain. This is a brand-name medication with no generic equivalent available.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy