Elotuzumab
Elotuzumab is a monoclonal antibody immunotherapy used to treat multiple myeloma. It works by targeting the SLAMF7 protein on cancer cells and activating natural killer cells to destroy myeloma cells. It is typically used in combination with other medications (lenalidomide or pomalidomide plus dexamethasone) for patients who have received at least one prior therapy.
Elotuzumab is an immunotherapy for multiple myeloma that helps the immune system identify and attack cancer cells.
Key facts at a glance
- ATC
- L01FX08
- RxNorm
- 1726104
- Generic
- Elotuzumab
- Class
- atc-l01
- Brands
- Empliciti
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- injection
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment of multiple myeloma in combination with lenalidomide and dexamethasone or pomalidomide and dexamethasone for patients who have received 1-3 prior therapies.
Elotuzumab is a humanized IgG1 monoclonal antibody that binds to the SLAMF7 protein on myeloma cells and natural killer cells, activating immune-mediated destruction of cancer cells.
Administered as an intravenous infusion. Common side effects include infusion-related reactions, fatigue, diarrhea, and fever. May increase risk of infections. Requires pre-medication with corticosteroids, antihistamines, and acetaminophen before infusion.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy