Fosaprepitant
Emend Injection is an antiemetic medication that helps prevent acute and delayed nausea and vomiting associated with chemotherapy and surgery. It contains the active ingredient fosaprepitant, a neurokinin-1 (NK-1) receptor antagonist that works by blocking substance P in the brain.
Anti-nausea medication used to prevent chemotherapy-induced and post-operative vomiting.
Key facts at a glance
- RxNorm
- 759503
- Generic
- Emend Injection
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Prevention of acute and delayed chemotherapy-induced nausea and vomiting (CINV) in combination with other antiemetics; prevention of postoperative nausea and vomiting (PONV).
Emend is an NK-1 receptor antagonist that blocks the action of substance P, a neuropeptide involved in triggering the vomiting reflex in the brain.
This is a brand-name medication administered intravenously by healthcare professionals. It is typically used alongside other antiemetics (such as 5-HT3 antagonists and corticosteroids) for optimal prevention of nausea and vomiting. Patients should inform their healthcare provider of all current medications due to potential drug interactions.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy